双线传奇私服-噬菌体联合方案可用于防治番茄青枯病

时间:2019-12-03 16:35 来源: www.seosem.ws

本期文章:《自然—生物技术》:Online/在线发表

南京农业大学沈其荣、韦中、Ville-Petri Friman等研究人员合作提出了针对番茄青枯病的噬菌体联合治疗方案。这一研究成果于12月2日在线发表于《自然—生物技术》。

研究人员研究了不同噬菌体组合对番茄青枯雷尔氏菌感染的生物防治功效。在单个作物季节的温室和田间试验中,增加组合噬菌体的数量可使疾病发生率降低多达80%。

疾病发生率降低的原因是病原体密度降低,以及筛选出了噬菌体抗药性但生长缓慢的病原体菌株,并且对青枯菌拮抗的细菌种类的富集。噬菌体处理不影响现有的根际微生物群。特定的噬菌体组合具有作为控制植物病原细菌工具的潜力。

据介绍,噬菌体被认为是可选的杀虫剂用于清除农作物的细菌病原体。但是,噬菌体生物防治的功效是不确定的,并且在自然的根际微生物群落中知之甚少。

附:英文原文

Title: Phage combination therapies for bacterial wilt disease in tomato

Author: Xiaofang Wang, Zhong Wei, Keming Yang, Jianing Wang, Alexandre Jousset, Yangchun Xu, Qirong Shen, Ville-Petri Friman

Issue&Volume: 2019-12-02

Abstract: Bacteriophages have been proposed as an alternative to pesticides to kill bacterial pathogens of crops. However, the efficacy of phage biocontrol is variable and poorly understood in natural rhizosphere microbiomes. We studied biocontrol efficacy of different phage combinations on Ralstonia solanacearum infection in tomato. Increasing the number of phages in combinations decreased the incidence of disease by up to 80% in greenhouse and field experiments during a single crop season. The decreased incidence of disease was explained by a reduction in pathogen density and the selection for phage-resistant but slow-growing pathogen strains, together with enrichment for bacterial species that were antagonistic toward R. solanacearum. Phage treatment did not affect the existing rhizosphere microbiota. Specific phage combinations have potential as precision tools to control plant pathogenic bacteria.

DOI: 10.1038/s41587-019-0328-3

Source: https://www.nature.com/articles/s41587-019-0328-3

期刊信息

Nature Biotechnology:《自然—生物技术》,创刊于1996年。隶属于施普林格·自然出版集团,最新IF:31.864
官方网址:https://www.nature.com/nbt/
投稿链接:https://mts-nbt.nature.com/cgi-bin/main.plex